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IKB-ε (D17) polyclonal antibody

货号: BS1191

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS1191

Product Name :IKB-ε (D17) polyclonal antibody

Swiss-Prot :O00221

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :IkB-ε (I-kappa-B-epsilon), also known as NFKBIE (NFκB inhibitor epsilon) or IKBE, is a 500 amino acid protein that belongs to the NFκB inhibitor family. Localizing to the cytoplasm, IkB-ε is highly expressed in spleen, testis and lung, with lower levels of expression found in kidney, pancreas, heart, placenta, brain, granulocytes and macrophages. IkB-ε inhibits c-Rel and NFκB subunits p50, p52 and p65 by forming a complex with them in the cytoplasm, preventing them from activating genes in the nucleus. IkB-ε undergoes serine phosphorylation, resulting in the protein being marked for destruction via the ubiquitination pathway.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IκB-ε (D17) polyclonal antibody detects endogenous levels of IκB-ε protein.

BiowMW :~ 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NF-kappa-BIE; I-kappa-B-epsilon; IkB-E; IkB-epsilon; IkappaBepsilon; NFKBIE; IKBE; IkB ε; IkBε

Immunogen :Synthetic peptide, corresponding to amino acids 1-50 of Human IKB-ε.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of IkB-ε (D17) polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:NIH-3T3 cell lysate Lane3:PC12 cell lysate

Immunohistochemistry (IHC) analyzes of IKB-ε (D17) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.