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Caveolin-1 (V163) polyclonal antibody（KU）

货号: BS1043

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS1043

Product Name :Caveolin-1 (V163) polyclonal antibody（KU）

Swiss-Prot :Q03135

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IF

Application_all :WB: 1:500~1:1000 IF: 1:50~1:200

Background :Caveolae (also known as plasmalemmal vesicles) are 50-100 nM flask-shaped membranes that represent a subcompartment of the plasma membrane. On the basis of morphological studies, caveolae have been implicated to function in the transcytosis of various macromolecules (including LDL) across capillary endothelial cells, uptake of small molecules via potocytosis, and the compartmentalization of certain signaling molecules, including G protein-coupled receptors. Three proteins, caveolin-1, caveolin-2 and caveolin-3, have been identified as principal components of caveolae. Two forms of caveolin-1, designated α and β, share a distinct but overlapping cellular distribution and differ by an amino-terminal 31 amino acid sequence which is absent from the β isoform. Caveolin-1 shares 31% identity with caveolin-2 and 65% identity with caveolin-3 at the amino acid level. Functionally, the three proteins differ in their interactions with heterotrimeric G protein isoforms.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Caveolin-1 (V163) polyclonal antibody detects endogenous levels of Caveolin-1 protein.

BiowMW :~ 20, 25 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Adherens Junction signaling,ErbB HER Signaling,

Alternative Name :Caveolin 1; Caveolin1; CAV1; CAV

Immunogen :Synthetic peptide, corresponding to amino acids 150-200 of Human Caveolin-1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Caveolin-1 (V163) polyclonal antibody at 1:500 dilution Lane1:A549 cell lysate Lane2:Mouse kidney tissue lysate Lane3:Rat kidney tissue lysate

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