Product Name :JTV1 polyclonal antibody
Reactivity :Human,Mouse,Rat
Application_all :WB: 1:500~1:1000
Background :JTV1, also known as P38 or AIMP2 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 2), is a 320 amino acid nuclear and cytoplasmic protein that is a component of the aminoacyl-tRNA synthase complex. Containing one GST C-terminal domain, JTV1 mediates ubiquitination and degradation of FBP1, a transcriptional activator of c-Myc, leading to c-Myc down-regulation, which is required for aveolar type II cell differentiation. JTV1 also participates in blocking MDM2-mediated ubiquitination, degradation of p53 and functions as a proapoptotic factor.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :JTV1 polyclonal antibody detects endogenous levels of JTV1 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Multisynthase complex auxiliary component p38; Protein JTV-1; AIMP2; JTV1; PRO0992
Immunogen :Recombinant full length Human JTV1.
Modification :Unmodification
