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ULK1 (S317) polyclonal antibody（KU）

货号: AP1005

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :AP1005

Product Name :ULK1 (S317) polyclonal antibody（KU）

Swiss-Prot :O75385

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :VPS34 (vacuolar protein sorting-associated protein 34), also known as VPT29, VPL7, PEP15 or END12, is a 875 amino acid peripheral membrane protein that localizes to the golgi apparatus. Belonging to the PI3/PI4-kinase family, VPS34 is involved in endosome-to-Golgi retrograde transport as part of the VPS34 PI3-kinase complex II. The VPS34 PI3-kinase complex II is required for the endosome-to-Golgi retrieval of PEP1 and KEX2, and the recruitment of VPS5 and VPS7, two components of the retromer complex, to endosomal membranes. It has been suggested that VPS34 may also be involved in ethanol tolerance and cell wall integrity.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :VPS34 polyclonal antibody detects endogenous levels of VPS34 protein.

BiowMW :~ 150 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :PI3K AKT signaling,Autophagy Signaling,MTOR signaling,

Alternative Name :Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC:2.7.1.137); PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; Phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; hVps34; PIK3C3;

Immunogen :A synthetic peptide corresponding to residues in Human VPS34.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of ULK1 polyclonal antibody at 1:1000 dilution Lane1:L02 whole cell lysate(20ug) Lane2:Panc1 whole cell lysate(20ug) Lane3:HEK293T whole cell lysate(40ug) Lane4:HCC827 whole cell lysate(40ug) Lane5:The Brain tissue lysate of Rat(40ug) Lane6:The Brain tissue lysate of Mouse(40ug)