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VEGF-A (L98) polyclonal antibody

货号: AP0742

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :AP0742

Product Name :VEGF-A (L98) polyclonal antibody

Swiss-Prot :P15692

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :VEGF is a dimeric glycoprotein with structural homology to PDGF. Several variants of VEGF have been described that arise by alternative mRNA splicing. It has been speculated that VEGF may function as a tumor angiogenesis factor in vivo because the expression pattern of VEGF is consistent with a role in embryonic angiogenesis. VEGF mRNA is formed in some primary tumors, VEGF is produced by tumor cell lines in vitro and VEGF mitogenic activity appears to be restricted to endothelial cells. A member of the PDGF receptor family, Flt, has been identified as a high-affinity receptor for VEGF.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :VEGF-A (L98) polyclonal antibody detects endogenous levels of total VEGF-A protein (13 isoforms).

BiowMW :~ 27 kDa (VEGF206); 45 kDa (L-VEGF206); ~ 15-44 kDa (Others Isoform)

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF; VEGFA; VEGF

Immunogen :Synthetic peptide, corresponding to amino acids 70-120 of Human VEGF206.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of VEGF-A (L98) pAb at 1:500 dilution Lane1:LOVO whole cell lysate(40ug) Lane2:Panc1 whole cell lysate(40ug) Lane3:CT26 whole cell lysate(40ug) Lane4:H9C2 whole cell lysate(40ug)

Synergistic anti-hepatoma effect of bufalin combined with sorafenib via mediating the tumor vascular microenvironment by targeting mTOR/VEGF signaling

JournalInternational Journal Of Oncology

ApplicationWB,IHC

IF3.899

SpeciesMouse

PMID29620259
KPT-330 and Y219 exert a synergistic anti-tumor effect in triple-negative breast cancer through inhibiting NF-κB signaling

JournalFEBS Open Bio

ApplicationWB

IF2.792

SpeciesHuman

PMID36847599