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Cox-4 polyclonal antibody（KU）

货号: AP0705

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :AP0705

Product Name :Cox-4 polyclonal antibody（KU）

Swiss-Prot :P13073

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Cytochrome c oxidase (COX) functions as the terminal oxidase of the respiratory chain that uses cytochrome c as an electron donor to drive a proton gradient across the inner mitochondrial membrane. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial encoded catalytic subunits and several nuclear gene encoded structural subunits. COX contains two iron-coordination sites and two copper-coordination sites. Cytochrome c oxidase IV (COX4) is a nuclear-encoded subunit of COX that may play a role in regulating COX activity. COX4 is expressed ubiquitously in adult human tissue with the strongest levels of expression in the pancreas and moderate expression levels in heart, skeletal muscle and placenta.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cox-4 polyclonal antibody detects endogenous levels of Cox-4 protein.

BiowMW :~ 20 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :AMPK Signaling Pathway,

Alternative Name :Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1; COX4I1; COX4

Immunogen :Recombinant full length Human Cox-4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Cox-4 pAb at 1:500 dilution Lane1:3T3-L1 whole cell lysate(40ug) Lane2:C6 whole cell lysate(40ug) Lane3:HCT116 whole cell lysate(10ug) Lane4:U-87MG whole cell lysate(10ug)

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