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PPAR-gama(Phospho-Ser276) polyclonal antibody（KU）

货号: AP0660

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :AP0660

Product Name :PPAR-gama(Phospho-Ser276) polyclonal antibody（KU）

Swiss-Prot :P37231

Host :Rabbit

Reactivity :Human,Rat

Applications :WB IF

Application_all :WB: 1:1000~1:2000 IF: 1:100~1:500

Background :Peroxisome proliferator-activated receptor γ (PPARγ) is a member of the ligand-activated nuclear receptor superfamily and functions as a transcriptional activator. PPARγ is preferentially expressed in adipocytes as well as in vascular smooth muscle cells and macrophage. Besides its role in mediating adipogenesis and lipid metabolism, PPARγ also modulates insulin sensitivity, cell proliferation and inflammation. PPARγ transcriptional activity is inhibited by MAP kinase phosphorylation of PPARγ at Ser84.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PPAR-gama(Phospho-Ser276) polyclonal antibody detects endogenous levels of PPAR-gama protein only when phosphorylated at Ser276.

BiowMW :~ 67 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :MAPK Erk in Growth and Differentiation Pathway(,MTOR signaling,

Alternative Name :Peroxisome proliferator-activated receptor gamma; Short name=PPAR-gamma; Nuclear receptor subfamily 1 group C member 3; PPARG; NR1C3; PPAR γ; PPARγ

Immunogen :Synthetic phosphopeptide derived from human PPAR-gama around the phosphorylation site of Serine 276.

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot (WB) analysis of PPAR-gama(Phospho-Ser276) polyclonal antibody at 1:1000 dilution Lane1:Hela whole cell lysate(30ug) Lane2:Hela treated with LPS(200 ng/ml,15 minutes) whole cell lysate(30ug) Lane3:PC12 whole cell lysate(30ug)